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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name hsa-miR-27a
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Homo sapiens
Tissues/Cell_line human retinal pigment epithelial (RPE)-1 cells
Methods MTT assay, qRT-PCR, transfection, Western blot, ELISA
Expression pattern down-regulated
Functional description miR-27a protects RPE cells subjected to high glucose via inhibiting inflammation and apoptosis through targeting TLR4.
PubMed ID 29896271
Year 2018
Title MicroRNA-27a protects retinal pigment epithelial cells under high glucose conditions by targeting TLR4.
Drug-related ncRNA NO

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