ncRNA name | hsa-miR-27a |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human retinal pigment epithelial (RPE)-1 cells |
Methods | MTT assay, qRT-PCR, transfection, Western blot, ELISA |
Expression pattern | down-regulated |
Functional description | miR-27a protects RPE cells subjected to high glucose via inhibiting inflammation and apoptosis through targeting TLR4. |
PubMed ID | 29896271 |
Year | 2018 |
Title | MicroRNA-27a protects retinal pigment epithelial cells under high glucose conditions by targeting TLR4. |
Drug-related ncRNA | NO |
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